A multi-feature and multi-channel univariate selection process for seizure prediction.
نویسندگان
چکیده
OBJECTIVE To develop a prospective method for optimizing seizure prediction, given an array of implanted electrodes and a set of candidate quantitative features computed at each contact location. METHODS The method employs a genetic-based selection process, and then tunes a probabilistic neural network classifier to predict seizures within a 10 min prediction horizon. Initial seizure and interictal data were used for training, and the remaining IEEG data were used for testing. The method continues to train and learn over time. RESULTS Validation of these results over two workshop patients demonstrated a sensitivity of 100%, and 1.1 false positives per hour for Patient E, using a 2.4s block predictor, and a failure of the method on Patient B. CONCLUSIONS This study demonstrates a prospective, exploratory implementation of a seizure prediction method designed to adapt to individual patients with a wide variety of pre-ictal patterns, implanted electrodes and seizure types. Its current performance is limited likely by the small number of input channels and quantitative features employed in this study, and segmentation of the data set into training and testing sets rather than using all continuous data available. SIGNIFICANCE This technique theoretically has the potential to address the challenge presented by the heterogeneity of EEG patterns seen in medication-resistant epilepsy. A more comprehensive implementation utilizing all electrode sites, a broader feature library, and automated multi-feature fusion will be required to fully judge the method's potential for predicting seizures.
منابع مشابه
MLIFT: Enhancing Multi-label Classifier with Ensemble Feature Selection
Multi-label classification has gained significant attention during recent years, due to the increasing number of modern applications associated with multi-label data. Despite its short life, different approaches have been presented to solve the task of multi-label classification. LIFT is a multi-label classifier which utilizes a new strategy to multi-label learning by leveraging label-specific ...
متن کاملDevelopment of an Ensemble Multi-stage Machine for Prediction of Breast Cancer Survivability
Prediction of cancer survivability using machine learning techniques has become a popular approach in recent years. In this regard, an important issue is that preparation of some features may need conducting difficult and costly experiments while these features have less significant impacts on the final decision and can be ignored from the feature set. Therefore, developing a machine for p...
متن کاملFeature Selection Using Multi Objective Genetic Algorithm with Support Vector Machine
Different approaches have been proposed for feature selection to obtain suitable features subset among all features. These methods search feature space for feature subsets which satisfies some criteria or optimizes several objective functions. The objective functions are divided into two main groups: filter and wrapper methods. In filter methods, features subsets are selected due to some measu...
متن کاملProposed Feature Selection for Dynamic Thermal Management in Multicore Systems
Increasing the number of cores in order to the demand of more computing power has led to increasing the processor temperature of a multi-core system. One of the main approaches for reducing temperature is the dynamic thermal management techniques. These methods divided into two classes, reactive and proactive. Proactive methods manage the processor temperature, by forecasting the temperature be...
متن کاملPrediction of Epileptic Seizures in Patients with Temporal Lobe Epilepsy (TLE) based on Cepstrum analysis and AR model of EEG signal
Epilepsy is a chronic disorder of brain function caused by abnormal and excessive electrical neurons discharge in the brain. Seizures cause disturbances in consciousness that occur without prior notice, so their prediction ability, based on EEG data, can reduce stress and improve quality of life. An epileptic patient EEG data consists of five parts: Ictal, Inter-Ictal, pre-Ictal, Post-Ictal, an...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
دوره 116 3 شماره
صفحات -
تاریخ انتشار 2005